Ethisev Tablet

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Ethisev Tablet

Generic Name: Etoricoxib + Thiocolchicoside

Thiocolchicoside
Etoricoxib

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Medicine Overview of Thiocolchicoside

Thiocolchicoside is a muscle relaxant & is used in the symptomatic treatment of painful muscle spasm.

THERAPEUTIC Class of Thiocolchicoside

Muscle Relaxant

Why Dusevis Prescribed

Thiocolchicoside prescribed for symptomatic treatment of painful muscle spasm.

When to Take

As advised by the physician.

How to Take

According to dosage form Thiocolchicoside is usually taken by the following route:
• Oral route
• Intravenous route

How it Works

Thiocholchicoside is a muscle relaxing agent that works through selective binding to the GABA-A receptor. It prevents muscle contractions by activating the GABA inhibitory motor pathway. It also has an affinity for the inhibitory glycine receptors (i.e., have glycomimetic and GABA mimetic activity), therefore acts as a muscle relaxant.

Warnings

Precautions

• Epileptic or have a risk of seizures
• Diarrhea during the administration of this product

Contraindications of Thiocolchicoside

Contraindicated in following condition:
• Flaccid paralysis
• Muscular hypotonia

Side Effects

Mild:
• Nausea
• Vomiting
• Diarrhea
• Abdominal pain
Serious:
• Drowsiness
• Skin rash
• Low blood pressure, a temporary blur of consciousness
• Swelling of the arms, legs, ankles, face, lips, or mouth, throat so that it causes difficulties in breathing or swallowing.
• Itching, swelling of the mucous membranes (angioneurotic edema)
• Fainting (vasovagal syncope)

Food to Avoid

If you are allergic to any food, please consult with the physician.
• Avoid alcohol
• Do not take with milk
• Take with food

Alcohol Interaction

Consumption of alcohol is not advisable.

Pregnancy / Lactation Protocol

Please consult with physician during pregnancy & lactation.

Storage

Store at room temperature.

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Medicine Overview of Etoricoxib

Etoricoxib, a selective cycloxygenase (Cox-2) inhibitor, used in treating bone and joint inflammation, gout.

THERAPEUTIC Class of Etoricoxib

Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)

Why Dusevis Prescribed

Treatment of:
• Pain and inflammation
• Joint pain
• Osteoarthritis
• Rheumatoid arthritis
• Ankylosing spondylitis

When to Take

As advised by the physician.

How to Take

According to the dosage forms the following routes of administration are available:
• Oral
• Parenteral

How it Works

Etoricoxib is a selective cyclooxygenase-2 (COX-2) inhibitor primarily responsible to reduce mediators of pain and inflammation. Its action is due to inhibition of prostaglandin synthesis via inhibition of COX-2.

Precautions

Report to the physician if the patients are allergic to the active ingredients and any other drugs. This includes:
• Telling about the history of current stomach ulcer or bleeding in stomach or intestines
• Serious liver disease
• Serious kidney disease

Contraindications of Etoricoxib

Inflammatory bowel disease, severe congestive heart failure, active peptic ulceration, cerebrovascular disease, lactation, children, adolescent < 16 years

Side Effects

Report to the physician immediately if the patients are having any of these following symptoms:
• Nausea
• Vomiting
• Heartburn
• Indigestion
• Uncomfortable feeling or pain in the stomach
• Diarrhoea
• Swelling of the legs
• Ankles or feet
• High blood pressure
• Dizziness
• Headache